Botox, Dysport, & Letybo: What’s the Difference and Which Is Right for You?

lindseyalbanohart
Aug 23
2 min read

When it comes to reducing fine lines and wrinkles, there are more options than ever before. Botox®, Dysport®, and the newly FDA-approved Letybo® are all neuromodulators that smooth expression lines by temporarily relaxing facial muscles. But with several choices available, how do you know which is best for you?

At Opal Medical Aesthetics, we specialize in helping you choose the right treatment for your goals. Here’s a breakdown of the similarities and differences.

What They All Have in Common

All three are neuromodulators made from botulinum toxin type A.
They work by relaxing targeted facial muscles, softening wrinkles caused by expressions like frowning, squinting, or raising your brows.
They are quick, minimally invasive procedures with little to no downtime.

Key Differences Between Botox, Dysport, and Letybo

1. Molecule Size and Spread

Botox: Larger molecular size, stays very localized—ideal for precise treatment of smaller areas.
Dysport: Spreads more easily, making it useful for larger treatment areas like the forehead.
Letybo: Has a similar mechanism to Botox but is designed for smooth, natural distribution with consistent results.

2. Onset of Results

Botox: Results appear in about 5–7 days.
Dysport: Often works faster, with results visible in 2–3 days.
Letybo: Clinical studies show results begin in about 3 days, with full effect by day 7.

3. Treatment Areas

Botox: Versatile—commonly used for crow’s feet, forehead lines, frown lines (“11s”), and more.
Dysport: Popular for treating moderate to severe frown lines between the brows.
Letybo: FDA-approved specifically for moderate to severe glabellar lines (frown lines) but emerging as a strong competitor for natural-looking results across multiple areas.

4. Duration

Botox: Typically lasts about 3–4 months.
Dysport: Lasts around 3–4 months; some patients report slightly longer duration.
Letybo: Studies suggest similar longevity to Botox, around 3–4 months.

Which One Is Right for You?

The choice depends on:

Your goals (precision vs. broader coverage vs. natural smoothness).
Your timeline (do you want faster onset before a special event?).
Your preferences (if one treatment hasn’t given you your desired results, another may).

At Opal Medical Aesthetics, we’ll tailor your treatment to your facial anatomy, lifestyle, and desired outcome—ensuring the most natural, refreshed version of you.

Final Thoughts

Whether you choose Botox, Dysport, or Letybo, each offers safe, effective, and natural-looking results when performed by a skilled provider. With more options available than ever, you can feel confident that there’s a perfect treatment to fit your needs.

✨ Ready to explore your options? Book a consultation today at Opal Medical Aesthetics and discover which neuromodulator is right for you.